Claudio

Computational Biologist & ML Researcher

I build models that bridge AI and biology, from generative modeling to omics-driven discovery.

About Me

Researcher. Problem-solver. Creative.

I'm a researcher with a PhD in computational biology. I focus on developing generative models and graph-based approaches to understand biological systems, particularly how different omics interact in space and disease to give rise to phenotypes.

I've designed deep learning models for multi-omics integration, worked with large-scale single-cell and spatial data, and explored optimal transport to disentangle disease mechanisms and enable biological discovery.

Skills & Tools

Python
PyTorch
Generative Models
Graph ML
Multi-Omics Integration
Spatial Transcriptomics
Optimal Transport
Git / GitHub

Featured Projects

Research & experiments I’m proud of

Graph ML for Metabolite Prediction

Designed a graph-based model using enzyme expression to infer metabolite abundance across subsystems, aiming to apply this framework to spatial transcriptomics.

Graph ML Multi-modal Metabolomics Spatial Transcriptomics

Modeling Cell-Cell Communication

Developed a spatially-aware model of ligand-receptor signaling in polycystic kidney disease (ADPKD)

Spatial data Tensor decomposition

spVIPES: shared-private Variational Inference with Product of Experts

I designed spVIPES, a model that disentangles biological variation. The architecture combines variational inference with a novel product-of-experts based alignment leveraging optimal transportto compare any two conditions.

Variational Inference Optimal Transport Disentanglement Generative ML

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Get In Touch

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GitHub

View my code